Highly sensitive dual mode dual side cross polarization converter based biosensor.

—This paper investigates a dual-side, dual-mode reflective cross-polarization converter for biosensing applications. The converter consists of a polyimide substrate with a modified dumbbell-shaped resonator on one surface and its complementary slot on another. The overall volume is 8.25μm × 8.25μm × 2.47 μm with dual-band operation of 6.39268–7.311692 THz and 9.783001–23.53473 THz for PCR≥80 % for front signal incidence and two full widths at half maximum (FWHM) bands i.e. 11.71594–12.26761 THz & 19.12042–19.87691 THz for back signal incidence. The periodicity is ∼λ o /6, and substrate thickness is ∼λ o /19 at 6.39268 THz. This device has performance stability for incident angle (θ)≤30o. The performance of this device can be tuned from dual-band operation to single-band by varying the chemical potential of the graphene strip for signal incidence from both sides. This device can classify cancer or tuberculosis-infected cells concerning healthy cells by using the variations in their corresponding refractive indices that lead to changes in the band edge frequencies. This device can differentiate between infected and healthy cells or different refractive indices with a high sensitivity of ∼5 THz/RIU. This device has merits of dual side sensing, wide operating bandwidth, multiple frequencies for sensing purposes, and high sensitivity over previously reported sensors. • Bi-directional Cross polarization converter with incident angle (θ) stability for θ≤30o, thickness and 8.25×8.25×2.47µm3. • Front signal has PCR≥80% for ∼6.39-7.32 THz & ∼9.78-23.53 THz. • Back signal has PCR≥50% for ∼11.72-12.27 THz & ∼19.12-19.88 THz. Graphene chemical potential reconfigures this to single band. • Can be used as Biosensor to detect cancer, tumour, malaria, tuberculosis, Leukemia with high sensitivity of ∼5 THz/RIU. • Proposed refractive index sensing method utilizes fL or fH instead of fr, resulting in more accurate sensing. [ABSTRACT FROM AUTHOR]