Arsenic-trioxide: T-wave alternans and torsades de pointes: case report.

A case report published in Reactions Weekly describes a man in his 30s who developed T-wave alternans and torsades de pointes (TdP) while being treated with arsenic trioxide for acute promyelocytic leukemia. The patient experienced loss of consciousness and had decreased levels of magnesium and ionized calcium. Electrocardiogram results showed an extended QTc interval and alternating T-wave polarity. The patient was diagnosed with life-threatening T-wave alternans and TdP secondary to arsenic trioxide and underwent cardioversion and received magnesium sulfate, although the outcome is not specified. [Extracted from the article]