Revealing the architecture of the membrane-bound Flotillin cage assembly.

This article provides an overview of the Flotillin cage, a protein complex found in various organisms, including humans. The Flotillin cage plays a role in several cellular processes, such as endocytosis, mitochondrial function, intracellular trafficking, and touch sensation. The study focuses on the structure of the Flotillin-1/Flotillin-2 complex, which forms a circular cage structure consisting of 22 heterodimers. The research paper cited, titled "In-situ architecture of the human prohibitin complex" by Lange et al., delves into the architecture and function of the human prohibitin complex, offering valuable insights. The citation provides links to access the full paper for further exploration. [Extracted from the article]