A Syringa pinnatifolia genome assembly reveals the zerumbone biosynthesis machinery with a cytochrome P450‐catalysed epoxidation reaction in eudicots.

This article presents a study on the genome assembly of Syringa pinnatifolia, a shrub valued in traditional Chinese medicine for its volatile chemical constituents. The researchers aimed to elucidate the biosynthesis pathway of zerumbone, a compound found in S. pinnatifolia with various medicinal properties. Through genome sequencing and analysis, they identified the genes responsible for the production of key compounds in the pathway, including a terpene synthase (TPS) gene and a cytochrome P450 (CYP450) gene. The study provides insights into the biosynthesis of zerumbone in eudicots and expands our understanding of the functions of TPS and CYP450 enzymes. [Extracted from the article]