Back to Search Start Over

Successes in translation.

Authors :
Westermark, Per
Merlini, Giampaolo
Source :
Amyloid. Sep2024, Vol. 31 Issue 3, p159-167. 9p.
Publication Year :
2024

Abstract

Translational research is key in advancing the diagnosis and therapy of systemic amyloidoses. This paper summarises our presentations at the ISA Workshop on Translation in Systemic Amyloidoses held in Athens on September 25-26, 2023. The critical advances made by the pioneers in the field are reviewed, with particular attention to the discoveries and developments of utmost importance to our understanding of what amyloid is and how the substance affects functions. Examples of translational research regarding the mechanisms of cardiac damage in light chain amyloidosis, the role of biomarkers in improving our understanding of the biology of the disease and patients' management, and the molecular mechanisms involved in the cytotoxicity are described. Advances in basic research continue to open new therapeutic avenues. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13506129
Volume :
31
Issue :
3
Database :
Academic Search Index
Journal :
Amyloid
Publication Type :
Academic Journal
Accession number :
179084889
Full Text :
https://doi.org/10.1080/13506129.2024.2387163