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A standardized clinical database for research in Chagas disease: The NHEPACHA network.
- Source :
-
PLoS Neglected Tropical Diseases . 8/15/2024, Vol. 18 Issue 8, p1-9. 9p. - Publication Year :
- 2024
-
Abstract
- The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research framework for Chagas disease that encompasses diagnosis and treatment. For this purpose, the network has created a questionnaire to gather relevant data on epidemiological, clinical, diagnostic, and therapeutic aspects of the disease. This questionnaire was developed based on a consensus of expert members of the network, with the intention of collecting high-quality standardized data, which can be used interchangeably by the different research centers that make up the NHEPACHA network. Furthermore, the network intends to offer a clinical protocol that can be embraced by other researchers, facilitating comparability among published studies, as well as the development of therapeutic response and progression markers. Author summary: In this work, we present a new clinical questionnaire for the standardized evaluation and collection of clinical data from patients with acute or chronic Trypanosoma cruzi infection, as well as a uniformed database to collect it. The questionnaire has been produced after consensus from clinical experts belonging to the NHEPACHA network, a coalition of clinical research institutions in Latin America and Spain. This tool will facilitate the collection and sharing of high-quality clinical and paraclinical data useful to annotate sample collections, and allow clinically meaningful comparisons between different cohorts. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19352727
- Volume :
- 18
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- PLoS Neglected Tropical Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 179043053
- Full Text :
- https://doi.org/10.1371/journal.pntd.0012364