Back to Search
Start Over
Nanosilver-based materials as feed additives: Evaluation of their transformations along in vitro gastrointestinal digestion in pigs and chickens by using an ICP-MS based analytical platform.
- Source :
-
Analytical & Bioanalytical Chemistry . Jul2024, Vol. 416 Issue 16, p3821-3833. 13p. - Publication Year :
- 2024
-
Abstract
- The use of a new nanomaterial in the feed chain requires a risk assessment that involves in vitro gastrointestinal digestions to predict its degradation and oral exposure to nanoparticles. In this study, a nanosilver-based material was incorporated into pig and chicken feed as a growth-promoting additive and subjected to the corresponding in vitro gastrointestinal digestions. An inductively coupled plasma mass spectroscopy (ICP-MS) analytical platform was used to obtain information about the silver released in the different digestion phases. It included conventional ICP-MS for total silver determination, but also single particle ICP-MS and coupling to hydrodynamic chromatography for detection of dissolved and particulate silver. The bioaccessible fraction in the intestinal phase accounted for 8–13% of the total silver, mainly in the form of dissolved Ag(I) species, with less than 0.1% as silver-containing particles. Despite the additive behaving differently in pig and chicken digestions, the feed matrix played a relevant role in the fate of the silver. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PLASMA spectroscopy
*MASS spectrometry
*CHICKENS
*DIGESTION
*SILVER
Subjects
Details
- Language :
- English
- ISSN :
- 16182642
- Volume :
- 416
- Issue :
- 16
- Database :
- Academic Search Index
- Journal :
- Analytical & Bioanalytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 178995536
- Full Text :
- https://doi.org/10.1007/s00216-024-05323-8