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Recent Progress in Photothermal, Photodynamic and Sonodynamic Cancer Therapy: Through the cGAS-STING Pathway to Efficacy-Enhancing Strategies.

Authors :
Fang, Kelan
Zhang, Huiling
Kong, Qinghong
Ma, Yunli
Xiong, Tianchan
Qin, Tengyao
Li, Sanhua
Zhu, Xinting
Source :
Molecules. Aug2024, Vol. 29 Issue 15, p3704. 16p.
Publication Year :
2024

Abstract

Photothermal, photodynamic and sonodynamic cancer therapies offer opportunities for precise tumor ablation and reduce side effects. The cyclic guanylate adenylate synthase-stimulator of interferon genes (cGAS-STING) pathway has been considered a potential target to stimulate the immune system in patients and achieve a sustained immune response. Combining photothermal, photodynamic and sonodynamic therapies with cGAS-STING agonists represents a newly developed cancer treatment demonstrating noticeable innovation in its impact on the immune system. Recent reviews have concentrated on diverse materials and their function in cancer therapy. In this review, we focus on the molecular mechanism of photothermal, photodynamic and sonodynamic cancer therapies and the connected role of cGAS-STING agonists in treating cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14203049
Volume :
29
Issue :
15
Database :
Academic Search Index
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
178948908
Full Text :
https://doi.org/10.3390/molecules29153704