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Clinicopathologic conference: Bloodstream infection in an allogeneic hamatopoietic cell transplant: Thinking beyond the usual.

Authors :
Yeoh, Kim
Lass‐Flörl, Cornelia
Lamoth, Frédéric
Slavin, Monica A
Williams, Eloise
Neofytos, Dionysios
Source :
Transplant Infectious Disease. Aug2024, Vol. 26 Issue 4, p1-6. 6p.
Publication Year :
2024

Abstract

This case involves a 53‐year‐old female with concurrent acute myeloid leukemia (AML) and multiple myeloma. She underwent cytarabine and daunorubicin (7+3) induction chemotherapy followed by cytarabine (HiDAC) consolidation, with an early AML relapse requiring azacitidine and venetoclax therapy. She achieved complete remission and incomplete count recovery. Following fludarabine, melphalan, and thymoglobulin induction chemotherapy, she underwent an allogeneic stem cell transplant with failure to engraft, requiring autologous stem cell rescue, buffy coat, and granulocyte transfusions, eventually presenting with a diffuse skin rash consistent with Steven‐Johnson syndrome and toxic epidermal necrolysis, persistent neutropenic fevers and positive blood cultures. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13982273
Volume :
26
Issue :
4
Database :
Academic Search Index
Journal :
Transplant Infectious Disease
Publication Type :
Academic Journal
Accession number :
178946338
Full Text :
https://doi.org/10.1111/tid.14273