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The people behind the papers - Alyshia Scholl, Yihong Liu and Geraldine Seydoux.

Source :
Development (09501991). Jul2024, Vol. 151 Issue 14, p1-2. 2p.
Publication Year :
2024

Abstract

A new study in the journal Development has found that many mRNAs enriched in germ granules in Caenorhabditis elegans are not involved in germline development. The researchers were surprised to find that most of the transcripts in germ granules encode general housekeeping functions and are degraded before the formation of primordial germ cells (PGCs). Only a small number of transcripts are maintained in PGCs and are required for germ cell fate. The researchers hypothesize that the majority of transcripts in germ granules function as structural scaffolds to support the condensation of the protein MEG-3, while only a minority of transcripts enrich in PGCs and play a role in germ cell fate determination. [Extracted from the article]

Details

Language :
English
ISSN :
09501991
Volume :
151
Issue :
14
Database :
Academic Search Index
Journal :
Development (09501991)
Publication Type :
Academic Journal
Accession number :
178903720
Full Text :
https://doi.org/10.1242/dev.204215