The kynurenine pathway and acquired premature ejaculation.

Premature ejaculation is a common male sexual dysfunction. It seriously afects the life quality of patient and the relationship with his spouse, and in the long run, it may lead to serious personal consequences such as distress, anxiety, and stress. The proportion of patients with acquired premature eeaculation is relatively high among premature eeaculation patients, and they are more wiiling to seek or plan to seek treatment. Existing researches have demonstrated that 5-hydroxytryptophan synthesis is important in the development of premature eeaculation. The kynurenine pathway, which is one of the tryptophan metabolic pathways, may be associated with the development of premature eeaculation. Currently, the relationship between this pathway and premature eeaculation remains largely uncharacterized. This article summarizes and reviews the relationship between the kynurenine pathway and acquired premature eeaculation. [ABSTRACT FROM AUTHOR]