Multiple drugs: DRESS syndrome : 11 case reports.

A retrospective study described 11 patients, aged 9-74 years, who developed DRESS syndrome while being treated with various drugs including allopurinol, carbamazepine, leflunomide, sodium-valproate, and sulfasalazine. The patients experienced symptoms of DRESS syndrome 2-8 weeks after starting treatment. Laboratory tests showed abnormal leukocyte counts, eosinophil counts, AST, and ALT levels. Treatment with prednisolone or ciclosporin resulted in improvement, but unfortunately, two patients later died from sepsis-nosocomial infection or myocardial infarction and heart failure. [Extracted from the article]