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Acylative and Silylative Dynamic Kinetic Resolutions of 6-Hydroxy-2 H -pyran-3(6 H)-one Catalyzed by Chiral Guanidines.
- Source :
-
Synlett . Aug2024, Vol. 35 Issue 13, p1591-1595. 5p. - Publication Year :
- 2024
-
Abstract
- Chiral guanidine-catalyzed acylative and silylative dynamic kinetic resolutions of 6-hydroxy-2 H -pyran-3(6 H)-one were achieved. We succeeded in developing a non-enzymatic acylative dynamic kinetic resolution of 6-hydroxy-2 H -pyran-3(6 H)-one with high enantioselectivity, which could be improved by recrystallization. In contrast, the non-enzymatic silylative dynamic kinetic resolution of 6-hydroxy-2 H -pyran-3(6 H)-one was accomplished with a moderate selectivity for the first time. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09365214
- Volume :
- 35
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Synlett
- Publication Type :
- Academic Journal
- Accession number :
- 178720410
- Full Text :
- https://doi.org/10.1055/a-2206-7545