Back to Search
Start Over
The role of multiparametric magnetic resonance ımaging in the diagnosis of granulomatous prostatitis mimicking prostate cancer.
- Source :
-
Abdominal Radiology . Jul2024, Vol. 49 Issue 7, p2305-2310. 6p. - Publication Year :
- 2024
-
Abstract
- Purpose: Aimed to investigate the role of multiparametric magnetic resonance imaging (mp-MRI) in the diagnosis of granulomatous prostatitis caused by intravesical Bacillus Calmette–Guérin (BCG). Methods: In this prospective, single-center study, 10 male patients who were given intravesical BCG due to intermediate- and high-risk bladder cancer were included. Before transurethral resection of bladder tumors (TURB), all patients were evaluated by mp-MRI, serum prostate-specific antigen (PSA), and digital rectal examination (DRE). Serum PSA levels and DRE findings were evaluated before and after intravesical BCG treatment. Prostate mp-MRI was performed for patients with elevated levels of serum PSA and/or with abnormal DRE findings. Then, MRI fusion + systematic prostate biopsy was performed. Demographic data of the patients before and after intravesical BCG were compared. Results: The average age of the patients was 66.9 years (55–87 years). While PSA was 1.7 ng/ml before intravesical BCG treatment, it was 4.3 ng/ml after intravesical BCG treatment (p = 0.005). PSA density (PSAD) was 0.04 and 0.10 before and after the treatment, respectively (p = 0.012). DRE findings of all patients were normal before the treatment. However, abnormal findings were detected in 80% of them after the treatment (p = 0.008). PI-RADS ≥ 3 lesions were found to be significantly higher in all patients after intravesical BCG (p = 0.004). Conclusion: Granulomatous prostatitis is a rare complication of intravesical BCG. High PSA, abnormal DRE, and PI-RADS ≥ 3 lesions detected after intravesical BCG should suggest granulomatous prostatitis and unnecessary biopsies may be avoided. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 2366004X
- Volume :
- 49
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Abdominal Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 178678121
- Full Text :
- https://doi.org/10.1007/s00261-024-04288-7