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Exploration of bioconvection flow for biological fluid with planktonic microorganism and thermal radiation: Drug carriers for tumor cells.

Authors :
Alqarni, Awatif J.
Elsaid, Essam M.
Al Qarni, A. A.
Mekheimer, Kh. S.
Abo-Elkhair, Rabea E.
Abdel-Wahed, Mohamed S.
Source :
Modern Physics Letters B. Jul2024, p1. 31p. 27 Illustrations.
Publication Year :
2024

Abstract

One of the most cutting-edge ways to combat cancerous cells is to use cell drug carriers. These microorganisms swarm affected cells, preventing them from spreading throughout the body when they come into contact with outside stimuli. This work proposes a new type of non-Newtonian fluid flow through microvessel contains oxytactic motile microorganisms beside nanoparticles. These microorganisms swim up the oxygen concentration gradient, they also are oxygen consumers. These microorganisms serve as drug carriers to attack and destroy hypoxic tumor cells. The movement of these items within a porous peristaltic conduit that a fluid supported by nanoparticles travels through is represented mathematically in this work. The mathematical model accounts for the impact of thermal radiation forces, thermophoresis force, and Brownian motion using the main governing equations describing this issue such as momentum, heat, concentration, microorganisms, and oxytactic microorganisms transportation, which are solved using the Adomian decomposition method. The findings concentrated on demonstrating the thermal and streamlined distribution behavior of the flow in the presence of microorganisms. These results were demonstrated through a series of graphs followed by analysis in detail. In summary, some important results were discovered from the physical analysis, such as an increase in effective thermal diffusivity while resisting the diffusivity of oxytactic microorganisms, which decays the microorganism’s dispersion. Furthermore, the non-Newtonian Sutterby parameter causes a temperature decrease in all conduit domains because it opposes fluid motion. This study is expected to offer further possibilities for enhancing drug-carrier applications in hypoxic tumor areas by gaining a better understanding of the blood flow characteristics in those places. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02179849
Database :
Academic Search Index
Journal :
Modern Physics Letters B
Publication Type :
Academic Journal
Accession number :
178663600
Full Text :
https://doi.org/10.1142/s0217984924505055