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Copper‐Catalyzed One‐Pot Three‐Component Aminophosphinoylation of 1,4‐Naphthoquinone.
- Source :
-
ChemistrySelect . 7/18/2024, Vol. 9 Issue 27, p1-5. 5p. - Publication Year :
- 2024
-
Abstract
- A copper‐catalyzed one‐pot three‐component aminophosphinoylation reaction of 1,4‐naphthoquinone with disubstituted phosphine oxides and arylamines has been developed. Various disubstituted phosphine oxides and arylamines with diverse structures and electronic properties can work smoothly with 1,4‐naphthoquinone, afforded a series of corresponding aminophosphinoylated 1,4‐naphthoquinones with up to 96 % isolated yield. The present method features easily available reagents, operational simplicity, broad substrate scope, high atom and step economy. The potential practicality of this protocol was further demonstrated by gram‐scale synthesis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ELECTRONIC structure
*PHOSPHINE oxides
*AROMATIC amines
Subjects
Details
- Language :
- English
- ISSN :
- 23656549
- Volume :
- 9
- Issue :
- 27
- Database :
- Academic Search Index
- Journal :
- ChemistrySelect
- Publication Type :
- Academic Journal
- Accession number :
- 178648519
- Full Text :
- https://doi.org/10.1002/slct.202401806