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Gastrointestinal tract perforation after radiofrequency ablation for hepatic tumor: Incidence and risk factors.
- Source :
-
European Journal of Radiology . Aug2024, Vol. 177, pN.PAG-N.PAG. 1p. - Publication Year :
- 2024
-
Abstract
- • GI tract perforation following RFA for liver tumors is rare but potentially fatal. • The small intestine is vulnerable to thermal injury resulting from RFA. • Patients receiving ablation for liver tumors in proximity to the small intestine require careful observation. We analyzed the incidence and mortality rate of gastrointestinal (GI) tract perforation after radiofrequency ablation (RFA) for hepatic tumors and assess its risk factors. This retrospective cohort study included 4799 patients with malignant tumors who underwent RFA (n = 7206). Sixty-nine cases of thermal injury to the GI tract were identified via a search of the electronic medical record system using index terms and divided into two groups according to the thermal injury with (n = 8) or without (n = 61) GI tract perforation based on follow-up CT reports. The risk factors for GI tract perforation were identified via multivariable logistic regression analysis using clinical, technical, and follow-up CT findings. The incidence of thermal injury to the GI tract and GI tract perforation was 0.96 % (69/7206) and 0.11 % (8/7206), respectively. The type of adjacent GI tract and history of diabetes mellitus differed significantly between the two groups (p < 0.05). The index tumor being located around the small intestine was the only significant risk factor for GI tract perforation after ablation (Odds ratio, 22.69; 95 % confidence interval, 2.59–198.34; p = 0.005 [reference standard, stomach]). All perforations were not identified on CT images immediately after RFA. The median time to detection was 20 days (range, 3–41 days). Two patients (25 %, 2/8) died due to perforation-related complications. GI tract perforation after RFA for hepatic tumors is rare; however, it is associated with high mortality. Thus, careful follow-up is required after RFA if the index tumor is located around the small intestine. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0720048X
- Volume :
- 177
- Database :
- Academic Search Index
- Journal :
- European Journal of Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 178537514
- Full Text :
- https://doi.org/10.1016/j.ejrad.2024.111560