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Parameter identifiability of a within-host SARS-CoV-2 epidemic model.
- Source :
-
Infectious Disease Modelling (2468-2152) . Sep2024, Vol. 9 Issue 3, p975-994. 20p. - Publication Year :
- 2024
-
Abstract
- Parameter identification involves the estimation of undisclosed parameters within a system based on observed data and mathematical models. In this investigation, we employ DAISY to meticulously examine the structural identifiability of parameters of a within-host SARS-CoV-2 epidemic model, taking into account an array of observable datasets. Furthermore, Monte Carlo simulations are performed to offer a comprehensive practical analysis of model parameters. Lastly, sensitivity analysis is employed to ascertain that decreasing the replication rate of the SARS-CoV-2 virus and curbing the infectious period are the most efficacious measures in alleviating the dissemination of COVID-19 amongst hosts. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 24682152
- Volume :
- 9
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Infectious Disease Modelling (2468-2152)
- Publication Type :
- Academic Journal
- Accession number :
- 178494992
- Full Text :
- https://doi.org/10.1016/j.idm.2024.05.004