Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.

Authors :: Van der Horst, Gijsbertus T.J.
Muijtjens, Manja
Kobayashi, Kumiko
Takano, Riya
Shin-ichiro Kanno
Takao, Masashi
de Wit, Jan
Verkerk, Anton
Eker, Andre P. M.
van Leenen, Dik
Buijs, Ruud
Bootsma, Dirk
Hoeijmakers, Jan H. J.
Yasui, Akira
Source :: Nature. 4/15/1999, Vol. 398 Issue 6728, p627. 4p. 18 Black and White Photographs, 2 Diagrams.
Publication Year :: 1999
Abstract: Presents research which concluded that the mammalian proteins Cry1 and Cry2 are essential for the maintenance of circadian rhythmicity. Models for biological clocks; Oscillation of molecular clocks; Study of mice lacking the proteins; Mice showing a sudden and complete loss of rhythmicity.