带状疱疹后遗神经痛疼痛矩阵的研究进展.

Postherpetic neuralgia (PHN) is a typical chronic neuropathic pain syndrome. Both peripheral and central nervous system mechanisms are believed to be involved in PHN, but the central nervous system-related brain network structure and function are not yet fully elucidated, limiting the study on the clinical analgesic drugs and other intervention strategies. In recent years, the research on pain matrix-related brain networks has helped to reveal the central nervous system regulation mechanism of pain, but there are few reports on the PHN pain matrix. This review summarizes the recent studies on the PHN pain matrix, retrospectively analyzes the functional and structural changes in specific pain-related brain regions, in order to provide the new insights for exploring the effective targeted analgesic treatments. [ABSTRACT FROM AUTHOR]