Neodymium vanadates/graphene aerogel hybrid nanocomposites: optical sensor for rapid detection of noradrenaline.

Central nervous diseases caused by noradrenaline (NA) have attained special attention. NA is involved in many different physiological functions that occur throughout the central nervous system, including modifying sensory input, attention regulation, arousal, and sleep regulation. Hence, rapid, precise, and trustworthy NA detection is crucial. Here we have created Nd(VO4)/GA nanocomposite for the sensitive and selective detection of noradrenaline. Successful fabrication of Nd(VO4)/GA nanocomposite was verified by using transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), x-ray photoelectron spectroscopy (XPS) and x-ray diffraction (XRD) techniques. Optical properties were evaluated by colorimetric and fluorometric detection using UV–Vis absorption and photoluminescence spectroscopy. The created sensor has demonstrated superior noradrenaline detection capabilities using fluorometry with an LOD of 48.48 nM in a wide linear range of 6–215 nM, and for colorimetry, the LOD and linear range were 33.89 nM and 10–80 nM. Furthermore, the manufactured sensor has demonstrated exceptional reproducibility, strong stability, anti-interference capabilities, and excellent repeatability for noradrenaline detection. [ABSTRACT FROM AUTHOR]