Type 1/17 CD103+CD4+ nasal‐resident memory T cells in non‐eosinophilic chronic rhinosinusitis with nasal polyps.

This article discusses the role of nasal tissue-resident memory T (TRM) cells in chronic rhinosinusitis (CRS) with nasal polyps. The study found that non-eosinophilic CRS (NECRS) is characterized by an abundance of CD69+CD103+ TRM cells, which produce type 1 and type 17 cytokines. These TRM cells may contribute to NECRS pathogenesis and could indicate difficult-to-treat cases. The findings provide new insights into the role of nasal-resident T cells in CRS and suggest potential therapeutic targets. [Extracted from the article]