Human adipose tissue expression of uncoupling protein 1 in response to intravenous administration of B‐type natriuretic peptide hormone: Results from a randomized controlled crossover study.

A recent study published in the journal Diabetes, Obesity & Metabolism investigated the effects of B-type natriuretic peptide (BNP) hormone on adipose tissue in humans. The study found that a 4-hour infusion of BNP led to a two- to five-fold increase in the expression of uncoupling protein 1 (UCP1), a marker of brown/beige adipocytes. This suggests that BNP may promote adipocyte thermogenesis and beiging, which could have implications for the treatment of obesity. The study had a small sample size and did not include women, so further research is needed to confirm these findings. [Extracted from the article]