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Clinical Outcomes of Complex Fractionated Atrial Electrogram Ablation and Box isolation for Persistent Atrial Fibrillation.
- Source :
-
Journal of Atrial Fibrillation & Electrophysiology . Jun2024, Vol. 17 Issue 2, p16-28. 13p. - Publication Year :
- 2024
-
Abstract
- We investigated whether posterior left atrial (LA) box isolation (BOXI) improved the rhythm outcome of catheter ablation in persistent atrial fibrillation (AF) when compared with complex fractionated atrial electrograms (CFAE) ablation. A total of 183 patients with persistent AF who underwent catheter ablation were recruited from the AF ablation registry database at Mie University Hospital; 68 patients underwent CFAE ablation, and 115 patients underwent BOXI. All patients underwent clinical review and 24-hour ambulatory ECG monitoring to detect asymptomatic arrhythmias at 1, 3, 6, and 12 months post-initial ablation. Patients in the BOXI group had a significantly higher freedom from AF rate than those in the CFAE group (81.5% vs 63.9%, p=0.014), with a similar trend in propensity score-matched patients (p=0.003). The BOXI procedure emerged as the only independent prognostic factor for freedom from AF recurrence. BOXI led to greater reduction in left atrial diameter from baseline to 3-6 months post-catheter ablation compared to CFAE ablation. Thus, BOXI may offer superiority over CFAE ablation in maintaining sinus rhythm in patients with persistent AF, in addition to pulmonary vein isolation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 28317335
- Volume :
- 17
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Atrial Fibrillation & Electrophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 178321922