РОЛЯ НА БИОМАРКЕРИТЕ В РАЦИОНАЛНАТА УПОТРЕБА НА ЛЕКАРСТВЕНИ ПРОДУКТИ.

The rational use of medicinal products is of fundamental importance for a successful and efficiently conducted therapy of the patient. Biomarkers have a crucial role in the rational use of medicines. They provide valuable information and help guide treatment decisions, optimize drug therapies, and improve patient outcomes. Aim: To analyse the role of biomarkers in the rational use of medicinal products. Methods and materials: The literature review was made through a documentary analysis of scientific statistics in the PubMed and Google Scholar platforms. Results: Biomarkers facilitate a personalized approach to drug therapy, improving rational use by providing guidance for accurate patient selection, making a more accurate diagnosis, choosing the appropriate drug according to the patient's condition, accurate dosing for a specific patient, reducing contraindications and risk from the occurrence of ADRs. Their use leads to savings for the health system created by unnecessary use of the wrong drugs, in the wrong quantities, for the wrong patient, and at the wrong time. As well as benefits, biomarkers also have their imperfections, so their application must be strictly monitored and controlled, and they must undergo serious study and validation. Conclusion: Biomarkers contribute significantly to increasing rational use, guiding healthcare professionals in making well-informed decisions about treatments tailored to individual patients, as long as they are wellstudied and their clinical relevance is demonstrated. [ABSTRACT FROM AUTHOR]