Ventrointermediate thalamic stimulation improves motor learning in humans.

Ventrointermediate thalamic stimulation (VIM-DBS) modulates oscillatory activity in a cortical network including primary motor cortex, premotor cortex, and parietal cortex. Here we show that, beyond the beneficial effects of VIM-DBS on motor execution, this form of invasive stimulation facilitates production of sequential finger movements that follow a repeated sequence. These results highlight the role of thalamo–cortical activity in motor learning. The authors show that ventrointermediate thalamic stimulation facilitates production of repeated sequential finger movements and modulates oscillatory cortical activity in the motor learning network, highlighting thalamo–cortical engagement in motor learning. [ABSTRACT FROM AUTHOR]