Back to Search Start Over

Kinetic Trapping of an Out‐of‐Equilibrium Dynamic Library of Imines by Changing Solvent.

Authors :
Valentini, Matteo
Ercolani, Gianfranco
Di Stefano, Stefano
Source :
Chemistry - A European Journal. 7/2/2024, Vol. 30 Issue 37, p1-6. 6p.
Publication Year :
2024

Abstract

A well‐behaved dynamic library composed of two imines and corresponding amines was subjected to the action of an activated carboxylic acid (ACA), whose decarboxylation is known to be base promoted, in different solvents, namely CD2Cl2, CD3CN, and mixtures of them. Two non‐equilibrium systems are consequently obtained: i) a dissipative (CD2Cl2) and ii) an out‐of‐equilibrium (CD3CN) dynamic library whose composition goes back to equilibrium after a given time. In the former case, the library is fully coupled with the decarboxylation of the ACA, while in the latter, an energy ratchet operates. In the mixed solvents, the library exhibits a mediated behavior. Interestingly, in the presence of an excess of added ACA, the different behavior of the imine library in the two solvents is expected to manifest only when the excess acid is consumed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09476539
Volume :
30
Issue :
37
Database :
Academic Search Index
Journal :
Chemistry - A European Journal
Publication Type :
Academic Journal
Accession number :
178211640
Full Text :
https://doi.org/10.1002/chem.202401104