Inhalational exposure history is associated with differential sinonasal gene expression profiles and clinical outcomes in chronic rhinosinusitis patients: A pilot study.

Authors :: Worden, Cameron P.
Thorp, Brian D.
Ebert, Charles S.
Klatt‐Cromwell, Cristine N.
Senior, Brent A.
Kimple, Adam J.
Rebuli, Meghan E.
Jaspers, Ilona
Source :: International Forum of Allergy & Rhinology. Oct2024, Vol. 14 Issue 10, p1652-1655. 4p.
Publication Year :: 2024
Abstract: Key points: Inhalational exposure (IE) history assessment is important and may guide chronic rhinosinusitis disease management.Combined exposure status was the most significant factor across differential gene expression analyseIE history was associated with pro‐inflammatory transcriptome changes and worse clinical outcomes. [ABSTRACT FROM AUTHOR]

Subjects :: *GENE expression profiling
*PARTICULATE matter
*AIR pollution
*GENE expression
*SINUSITIS

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