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Acetaminophen induced high anion gap metabolic acidosis: a potentially under-recognized consequence from a common medication.
- Source :
-
Pediatric Nephrology . Jul2024, p1-3. - Publication Year :
- 2024
-
Abstract
- While metabolic acidosis is one of the most common complications in patients with chronic kidney disease (CKD), there are several uncommon etiologies that are challenging to diagnose. Here, we describe a patient on peritoneal dialysis who developed high anion gap metabolic acidosis secondary to acquired 5-oxoprolinemia from acetaminophen use. While CKD is a known risk factor for developing this potentially serious complication, this case further highlights how 5-oxoproline accumulation can occur, even with therapeutic dosing of acetaminophen. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ACIDOSIS
*ACETAMINOPHEN
*ACID-base imbalances
*CHRONIC kidney failure
*DRUGS
*ANIONS
Subjects
Details
- Language :
- English
- ISSN :
- 0931041X
- Database :
- Academic Search Index
- Journal :
- Pediatric Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 178204660
- Full Text :
- https://doi.org/10.1007/s00467-024-06396-4