Farmacodermias: ¿cuántas y cuáles?

OBJECTIVES: To determine the frequency of pharmacodermias in the Hospital Ángeles Metropolitano, Mexico City, as well as to examine the clinical characteristics and etiological agents. MATERIALS AND METHODS: An observational, descriptive, cross-sectional and retrospective study was carried out from March 2022 to June 2023. Patients hospitalized at the Hospital Ángeles Metropolitano, Mexico City, over 18 years of age, with a diagnosis of mucocutaneous adverse drug reactions were included. RESULTS: Of the 16,651 hospitalized patients in the period of study, 104 were selected for diagnosis of mucocutaneous adverse drug reaction. The prevalence was of 6.24/1000 hospitalized patients, with a predominance of female sex (62.5%). The most frequent pharmacodermia was maculopapular exanthema, followed by urticaria with or without angioedema. Serious adverse drug reactions, such as Stevens-Johnson syndrome, accounted for 1%. The most related drugs were antibiotics, followed by nonsteroidal anti-inflammatory drugs. CONCLUSIONS: The results of this study agree with those reported in the national and international literature; however, epidemiological studies on pharmacodermias in Mexico should be continued in order to establish a more realistic national incidence. [ABSTRACT FROM AUTHOR]