APTAMER TABANLI TANIMLAMA YÖNTEMİ VE GIDA GÜVENLİĞİNDEKİ UYGULAMALARI.

Aptamers are single-stranded, short, synthetic nucleic acid sequences. Aptamers, which show high affinity and specific binding to various target molecules, are used for the sensitive detection of various risk factors such as pathogenic microorganisms, biotoxins, allergens, pesticides and heavy metals that may be present in foods. The selection of aptamers specifically binding to molecules that pose a risk in terms of food safety is carried out through a process called SELEX. The selected aptamer interacts specifically with the target molecule and this interaction is measured using electrochemical, optical, or other biosensor techniques. There is a growing interest in aptamer-based methods with high specificity and sensitivity, which provide faster results compared to conventional methods used in food analysis. This review summarized the general properties of aptamers and their production by the SELEX principle and given examples of their applications in food safety. [ABSTRACT FROM AUTHOR]