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Temperature Control of the Self‐Assembly Process of 4‐Aminoquinoline Amphiphile: Selective Construction of Perforated Vesicles and Nanofibers, and Structural Restoration Capability.
- Source :
-
Chemistry - A European Journal . 6/25/2024, Vol. 30 Issue 36, p1-11. 11p. - Publication Year :
- 2024
-
Abstract
- The construction of diverse and distinctive self‐assembled structures in water, based on the control of the self‐assembly processes of artificial small molecules, has received considerable attention in supramolecular chemistry. Cage‐like perforated vesicles are distinctive and interesting self‐assembled structures. However, the development of self‐assembling molecules that can easily form perforated vesicles remains challenging. This paper reports a lower critical solution temperature (LCST) behavior‐triggered self‐assembly property of a 4‐aminoquinoline (4‐AQ)‐based amphiphile with a tetra(ethylene glycol) chain, in HEPES buffer (pH 7.4). This property allows to form perforated vesicles after heating at 80 °C (> LCST). The self‐assembly process of the 4‐AQ amphiphile can be controlled by heating at 80 °C (> LCST) or 60 °C (< LCST). After cooling to room temperature, the selective construction of the perforated vesicles and nanofibers was achieved from the same 4‐AQ amphiphile. Furthermore, the perforated vesicles exhibited slow morphological transformation into intertwined‐like nanofibers but were easily restored by brief heating above the LCST. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 30
- Issue :
- 36
- Database :
- Academic Search Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 178095760
- Full Text :
- https://doi.org/10.1002/chem.202400134