Incidence, Risk Factors and Out Come of AKI In Patient Undergoing CABG in South Rajasthan.

Background: Acute kidney injury (AKI) is a common complication following coronary artery bypass grafting (CABG) surgery, particularly in older patients. The use of cardiopulmonary bypass (CPB) during CABG has been associated with an increased risk of AKI. Additionally, the type and volume of intravenous fluids administered during surgery may influence the occurrence of AKI. However, the impact of these factors on AKI in older patients undergoing CABG remains unclear. Method: This observational study conducted at a tertiary care center focused on patients undergoing coronary artery bypass grafting (CABG) surgery over an 18-month period. Included were adult patients aged 41 to 70, of any gender, diagnosed with triple vessel, double vessel, or single vessel illness, scheduled for on-pump CABG surgery, and classified as American Society of Anesthesiologists (ASA) II and III physical status. Exclusions comprised patients with specific preoperative serum creatinine levels, those below 40 or above 70 years, pre-existing kidney conditions, pregnancy, and unwillingness to participate. Result: The study included 58 participants with a mean age of 62.18 ± 8.01 years, predominantly male (76.7%). Among them, 42.2% experienced AKI postoperatively, with the majority classified as Stage 1 (37.1%). Serum creatinine levels showed a slight increase at 24 hours post-operation and a subsequent decrease at 48 hours. There was no significant association between AKI and age, gender, comorbidities, or intraoperative parameters including CPB duration and fluid administration. Conclusion: The study findings suggest that older patients undergoing onpump CABG are at increased risk of AKI, with chloride-rich fluids being an independent predictor. However, AKI was not associated with negative outcomes or mortality in this population. Further research is needed to explore strategies for mitigating AKI in older CABG patients, including optimizing fluid management and considering alternative surgical techniques. [ABSTRACT FROM AUTHOR]