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Intestinal linoleic acid contributes to the protective effects of Akkermansia muciniphila against Listeria monocytogenes infection in mice.

Authors :
Jin, Tong
Zhang, Yingying
Yang, Yanpeng
Teng, Yue
Yan, Chunhong
Shan, Zhongguo
Meng, Jianghong
Xia, Xiaodong
Source :
iMeta. Jun2024, Vol. 3 Issue 3, p1-8. 8p.
Publication Year :
2024

Abstract

This article explores the role of Akkermansia muciniphila, a type of gut bacteria, in preventing Listeria monocytogenes infection in mice. The study found that mice treated with A. muciniphila had reduced bacterial loads and improved intestinal barrier function compared to control mice. A. muciniphila was also found to increase levels of linoleic acid in the intestines, which strengthened the epithelial barrier and protected against L. monocytogenes infection. These findings suggest that A. muciniphila or linoleic acid-based strategies could be potential approaches for preventing listeriosis. [Extracted from the article]

Details

Language :
English
ISSN :
27705986
Volume :
3
Issue :
3
Database :
Academic Search Index
Journal :
iMeta
Publication Type :
Academic Journal
Accession number :
177945789
Full Text :
https://doi.org/10.1002/imt2.196