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Renewable risk assessment of heterogeneous streaming time‐to‐event cohorts.

Authors :
Ding, Jie
Li, Jialiang
Wang, Xiaoguang
Source :
Statistics in Medicine. 9/10/2024, Vol. 43 Issue 20, p3761-3777. 17p.
Publication Year :
2024

Abstract

The analysis of streaming time‐to‐event cohorts has garnered significant research attention. Most existing methods require observed cohorts from a study sequence to be independent and identically sampled from a common model. This assumption may be easily violated in practice. Our methodology operates within the framework of online data updating, where risk estimates for each cohort of interest are continuously refreshed using the latest observations and historical summary statistics. At each streaming stage, we introduce parameters to quantify the potential discrepancy between batch‐specific effects from adjacent cohorts. We then employ penalized estimation techniques to identify nonzero discrepancy parameters, allowing us to adaptively adjust risk estimates based on current data and historical trends. We illustrate our proposed method through extensive empirical simulations and a lung cancer data analysis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02776715
Volume :
43
Issue :
20
Database :
Academic Search Index
Journal :
Statistics in Medicine
Publication Type :
Academic Journal
Accession number :
179110193
Full Text :
https://doi.org/10.1002/sim.10146