The fatal case of "Pigmentibacter" bacteremia following aspiration pneumonia in elderly patient.

" Pigmentibacter ruber " was first reported in 2021, a novel bacterium of the family Silvanigrellaceae , isolated from human blood of the patient with aspiration pneumonia after the drowning accident in Republic of China. However, until now, there is only one report describing " P. ruber " infection, and no case of isolation from natural environment has been reported so far. Thus, the infectivity and pathogenicity of " Pigmentibacter " spp. has not been clearly understood. In this report, we described the fatal case of " Pigmentibacter " bacteremia subsequently occurred after aspiration pneumonia probably due to accidental ingestion of irrigation water in the elderly patient. Despite administration of broad-spectrum antibiotic, the patient dramatically deteriorated and eventually deceased. Whole-genome sequencing showed the strain isolated from the patient was identified as " Pigmentibacter " sp. (designated as strain Takaoka) and antimicrobial sensitivity testing showed it displayed high minimum inhibitory concentrations against various antibiotics including β-lactam. Further studies are needed to clarify the clinical characteristics of " Pigmentibacter " and its relative's infections and their antimicrobial sensitivity; however, the present case supported the clinical characteristics of " Pigmentibacter " infection , which can lead to bacteremia following aspiration pneumonia caused by mis-swallowing contaminated water, and poor outcome potentially due to multidrug resistances. [ABSTRACT FROM AUTHOR]