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Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine.

Authors :
Egwu, Chinedu O.
Aloke, Chinyere
Onwe, Kenneth T.
Umoke, Chukwunalu Igbudu
Nwafor, Joseph
Eyo, Robert A.
Chukwu, Jennifer Adaeze
Ufebe, Godswill O.
Ladokun, Jennifer
Audu, David Tersoo
Agwu, Anthony O.
Obasi, David Chukwu
Okoro, Chukwuemeka O.
Source :
Molecules. Jun2024, Vol. 29 Issue 11, p2584. 23p.
Publication Year :
2024

Abstract

There is a myriad of diseases that plague the world ranging from infectious, cancer and other chronic diseases with varying interventions. However, the dynamism of causative agents of infectious diseases and incessant mutations accompanying other forms of chronic diseases like cancer, have worsened the treatment outcomes. These factors often lead to treatment failure via different drug resistance mechanisms. More so, the cost of developing newer drugs is huge. This underscores the need for a paradigm shift in the drug delivery approach in order to achieve desired treatment outcomes. There is intensified research in nanomedicine, which has shown promises in improving the therapeutic outcome of drugs at preclinical stages with increased efficacy and reduced toxicity. Regardless of the huge benefits of nanotechnology in drug delivery, challenges such as regulatory approval, scalability, cost implication and potential toxicity must be addressed via streamlining of regulatory hurdles and increased research funding. In conclusion, the idea of nanotechnology in drug delivery holds immense promise for optimizing therapeutic outcomes. This work presents opportunities to revolutionize treatment strategies, providing expert opinions on translating the huge amount of research in nanomedicine into clinical benefits for patients with resistant infections and cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14203049
Volume :
29
Issue :
11
Database :
Academic Search Index
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
177861830
Full Text :
https://doi.org/10.3390/molecules29112584