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The Use of Compounds Derived from Cannabis sativa in the Treatment of Epilepsy, Painful Conditions, and Neuropsychiatric and Neurodegenerative Disorders.

Authors :
Stasiłowicz-Krzemień, Anna
Nogalska, Wiktoria
Maszewska, Zofia
Maleszka, Mateusz
Dobroń, Maria
Szary, Agnieszka
Kępa, Aleksandra
Żarowski, Marcin
Hojan, Katarzyna
Lukowicz, Malgorzata
Cielecka-Piontek, Judyta
Source :
International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5749. 46p.
Publication Year :
2024

Abstract

Neurological disorders present a wide range of symptoms and challenges in diagnosis and treatment. Cannabis sativa, with its diverse chemical composition, offers potential therapeutic benefits due to its anticonvulsive, analgesic, anti-inflammatory, and neuroprotective properties. Beyond cannabinoids, cannabis contains terpenes and polyphenols, which synergistically enhance its pharmacological effects. Various administration routes, including vaporization, oral ingestion, sublingual, and rectal, provide flexibility in treatment delivery. This review shows the therapeutic efficacy of cannabis in managing neurological disorders such as epilepsy, neurodegenerative diseases, neurodevelopmental disorders, psychiatric disorders, and painful pathologies. Drawing from surveys, patient studies, and clinical trials, it highlights the potential of cannabis in alleviating symptoms, slowing disease progression, and improving overall quality of life for patients. Understanding the diverse therapeutic mechanisms of cannabis can open up possibilities for using this plant for individual patient needs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16616596
Volume :
25
Issue :
11
Database :
Academic Search Index
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
177850474
Full Text :
https://doi.org/10.3390/ijms25115749