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The effect of sustainable low-dose sildenafil and cognitive-behavioral training on sexual function in methadone-treated men–a randomized controlled trial.
- Source :
-
Journal of Addictive Diseases . Jul-Sep2024, Vol. 42 Issue 3, p230-237. 8p. - Publication Year :
- 2024
-
Abstract
- Sexual dysfunction caused by opioids is one of the serious problems of drug misusers. This study aimed to evaluate and compare the effect of continuous low-dose sildenafil treatment alongside psychological training on the sexual function of methadone-treated patients. This randomized clinical trial was conducted on methadone-treated men with sexual dysfunction. Patients were randomly divided into two treatment groups: sildenafil 25 mg and psychological training. Sexual Quality of Life-Men, Sexual Self-Efficacy Scale–Erectile, and the International Index of Erectile Function were used before and 4 weeks after the end of the intervention. A total of 67 couples were included in the study (34 psychological interventions vs. 33 sildenafil group). After 4 weeks of treatment, the mean of male erectile function (33.73 ± 8.114 and 27.62 ± 6.238, p = 0.003) and sexual self-efficacy score (78.36 ± 12.713 and 69.62 ± 14.940, p < 0.0001) in the sildenafil group were statistically significant compared to the psychological group, however, the sexual quality score of the two groups was not statistically significant (31.48 ± 9.216 and 31.71 ± 11.333, p = 0.342). The sexual function of methadone-treated men in both groups was significantly improved, yet this difference was significantly greater in the pharmaceutical treatment group than the trainings. As a result, due to the high need for treatment, any type of intervention (medication or psychotherapy) will be effective in these patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- *METHADONE hydrochloride
*RESEARCH funding
*STATISTICAL sampling
*QUESTIONNAIRES
*TREATMENT effectiveness
*RANDOMIZED controlled trials
*MALE reproductive organ diseases
*PRE-tests & post-tests
*SEXUAL dysfunction
*DOSAGE forms of drugs
*SILDENAFIL
*COGNITIVE therapy
*COMPARATIVE studies
*GENETIC techniques
*BEHAVIOR therapy
*PHARMACODYNAMICS
Subjects
Details
- Language :
- English
- ISSN :
- 10550887
- Volume :
- 42
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Addictive Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 177840364
- Full Text :
- https://doi.org/10.1080/10550887.2023.2186763