Andexanet-alfa: Myocardial infarction and stroke.

An 85-year-old woman experienced a stroke and myocardial infarction while being treated with andexanet alfa to reverse the effects of apixaban. The woman had a history of atrial fibrillation and was taking apixaban. After receiving andexanet alfa in the ICU, she developed confusion and chest discomfort. Physical examination revealed left-sided hemineglect, and further tests showed elevated Troponin-T levels and ST elevation. MRI results indicated multiple acute embolic strokes. The woman ultimately passed away, but the cause of death was not specified. [Extracted from the article]