When is the optimal time to stop continuous renal replacement therapy in children?

The article discusses the optimal timing for discontinuing continuous renal replacement therapy (CRRT) in children with severe acute kidney injury (AKI). The authors highlight the lack of guidance on this topic and the need for better criteria for stopping CRRT. They present data from a study that identified factors associated with successful liberation from CRRT in children, including higher vasoactive-inotropic scores, shorter CRRT duration, and higher urine output prior to CRRT initiation. The authors also discuss the challenges of managing CRRT in children and the potential implications of prolonged CRRT. Further research is needed to determine the best criteria for discontinuing CRRT in pediatric patients. [Extracted from the article]