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Kütle Spektrometresinden Glikan Mikrodizilerine: Glikomikte Analitik Tekniklere Genel Bir Bakış.

Authors :
Tekin, Burcu
Gurbanov, Rafig
Source :
Bilecik Seyh Edebali University Journal of Science / Bilecik Şeyh Edebali Üniversitesi Sosyal Bilimler Dergisi. 2024, Vol. 11 Issue 1, p218-235. 18p.
Publication Year :
2024

Abstract

Glycans, complex carbohydrate molecules, play crucial roles in various biological processes, significantly affecting health and disease. The comprehensive analysis of glycans requires a combination of advanced analytical techniques. This review provides a detailed workflow of the various methods employed in glycan analysis, including sample preparation, glycan enrichment, glycan release, labeling, separation, and detection. Each step's principles, applications, and advantages are described, highlighting their contributions to glycan research. Additionally, the review emphasizes the importance of selecting appropriate techniques for specific glycan analysis goals. The workflow provides a comprehensive understanding of glycans, unraveling their roles in biological systems and facilitating the development of novel therapeutic interventions. [ABSTRACT FROM AUTHOR]

Details

Language :
Turkish
ISSN :
24587575
Volume :
11
Issue :
1
Database :
Academic Search Index
Journal :
Bilecik Seyh Edebali University Journal of Science / Bilecik Şeyh Edebali Üniversitesi Sosyal Bilimler Dergisi
Publication Type :
Academic Journal
Accession number :
177768694
Full Text :
https://doi.org/10.35193/bseufbd.1322614