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Rapid electrodeposition of Cu nanoparticle film on Ni foam as an integrated 3D free-standing electrode for non-invasive and non-enzymatic creatinine sensing.
- Source :
-
Analyst . 5/21/2024, Vol. 149 Issue 10, p2905-2914. 10p. - Publication Year :
- 2024
-
Abstract
- High cost, inherent destabilization, and intricate fixing of enzyme molecules are the main drawbacks of enzyme-based creatinine sensors. The design of a low-cost, stabilizable, and enzyme-free creatinine sensing probe is essential to address these limitations. In this work, an integrated three-dimensional (3D) free-standing electrode was designed to serve as a non-enzymatic creatinine sensing platform and was fabricated by rapid electrodeposition of a dense copper nanoparticle film on nickel foam (Cu NP film/NF). This low-cost, stable, easy-to-fabricate, and binder-free Cu NP film/NF electrode has abundant active sites and excellent electrochemical performance. Cyclic voltammetry measurements show a wide linear range (0.25–24 mM), low detection limit (0.17 mM), and high sensitivity (306 μA mM−1 cm−2). The developed sensor shows high recovery of creatinine concentration in real urine. Besides, it has better specificity, reproducibility, and robustness in detecting creatinine. These excellent results suggest that a non-enzymatic creatinine sensor based on an integrated 3D free-standing Cu NP film/NF electrode has good potential for non-invasive detection of urinary creatinine. [ABSTRACT FROM AUTHOR]
- Subjects :
- *COPPER
*NANOPARTICLES
*CREATININE
*NICKEL films
*FOAM
*COPPER films
*ELECTROPLATING
Subjects
Details
- Language :
- English
- ISSN :
- 00032654
- Volume :
- 149
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Analyst
- Publication Type :
- Academic Journal
- Accession number :
- 177725137
- Full Text :
- https://doi.org/10.1039/d4an00162a