Eight quick tips for including chromosome X in genome-wide association studies.

This document provides tips and guidance for researchers conducting association analyses on chromosome X. It emphasizes the importance of including chromosome X in genetic studies and highlights the need for diverse statistical models to account for its unique characteristics, such as X inactivation and the hemizygous state in individuals with an XY karyotype. The document suggests retaining chromosome X variants in quality control pipelines, imputing chromosome X variants, and using genetic association software that supports X chromosome testing. It also encourages researchers to share their results and code with the scientific community to facilitate replication and further analysis. The document acknowledges the challenges associated with analyzing chromosome X but highlights the potential for future scientific discoveries in this field. [Extracted from the article]