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Manasamitra Vatakam on Scopolamine-Induced Amnesia in Female Wistar Rats.

Authors :
A., Sankar
Kandasamy, Deepa
Jones, Sumathi
Radhakrishan, Anjuna
C. S., Janaki
Sheriff, Dhastangir
K., Prabhu
Source :
Journal of Pharmacy & Bioallied Sciences. 2024 Supplement, Vol. 16, pS1824-S1828. 5p.
Publication Year :
2024

Abstract

Background: Neurodegenerative diseases induce amnesia, and effective treatment is still elusive. Aims and Objectives: The present study highlights the ameliorating effects of Manasa Mitra Vatakam (MMV) using behavioral parameters on scopolamine-induced memory loss in female Wistar rats. Materials and Methods: MMV was compared with DPZ as a standard in the present study to determine the behavioral parameters through elevated plus maze (Hebb William maze/rectangular maze)and locomotor activity in scopolamineinduced memory loss in female Wistar rats. Results and Discussion: The results of the study illustrate the effectiveness of MMV in reversing memory dysfunction and memory-enhancing effects. Conclusion: The study paves the way for exploring research in CNS disorders and its potential application in drug-induced neurotoxicity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09764879
Volume :
16
Database :
Academic Search Index
Journal :
Journal of Pharmacy & Bioallied Sciences
Publication Type :
Academic Journal
Accession number :
177693733
Full Text :
https://doi.org/10.4103/jpbs.jpbs_9_24