A pediatric case of KMT2A-rearranged B-lymphoblastic lymphoma treated with high-risk therapy.

This article discusses a pediatric case of KMT2A-rearranged B-lymphoblastic lymphoma, a rare type of non-Hodgkin lymphoma in children. The KMT2A gene rearrangements are commonly found in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), but are rarely described in lymphomas. The patient in this case had a mass on his back, which was surgically removed and diagnosed as B-lymphoblastic lymphoma. The presence of a KMT2A-rearrangement led to the decision to treat the patient with high-risk chemotherapy. The article emphasizes the need for further research to determine the best treatment approach for this type of lymphoma. [Extracted from the article]