Can we use PET to quantify mu opioid receptors across the monkey brain, spinal cord and peripheral organs at the same time? Totally!

The article discusses the development and benefits of total body positron emission tomography (PET) scanners, which have an extended axial field of view and improved sensitivity compared to traditional scanners. These scanners allow for simultaneous imaging of the entire body, resulting in higher sensitivity, improved signal-to-noise ratio, shorter scan times, and the ability to conduct pediatric scans without anesthesia. The article highlights the clinical and research applications of total body PET scanners, including the quantification of mu-opioid receptors in the monkey brain, spinal cord, and peripheral organs. The study demonstrates the feasibility and advantages of using total body PET scanners for preclinical research. [Extracted from the article]