Saccadic fatigue as an early indicator for diagnosing myasthenia gravis.

This article discusses the use of video-oculography (VOG) as a diagnostic tool for myasthenia gravis (MG), a neuromuscular disorder characterized by muscle weakness and fatigue. The case study presented describes a young male patient with intermittent double vision, which improved with rest and closure of either eye. Despite negative results from standard diagnostic tests, an in-depth VOG assessment revealed significant oculomotor fatigability during repetitive saccadic movements at higher frequencies. The patient was diagnosed with probable MG and started on medication, resulting in symptom improvement. The study suggests that VOG testing at higher saccade frequencies could enhance diagnostic accuracy for MG. [Extracted from the article]