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How to minimize the dropout and crossover in an infertility trial?

Authors :
Huang, Hao
Kuang, Hongying
Thomas, Tracey R.
Wei, Daimin
Zhang, Heping
Source :
Fertility & Sterility. Jun2024, Vol. 121 Issue 6, p905-908. 4p.
Publication Year :
2024

Abstract

Randomized controlled trials and intent-to-treat analyses are important for infertility clinical studies. Dropouts or crossovers during the study process will disrupt the randomization design and affect the intent-to-treat analysis. In this review, we have briefly introduced the occurrence of dropout and crossover from our previous Reproductive Medicine Network and other related studies and provided some experience obtained from these studies on how to minimize and reduce the occurrence of dropout and crossover for infertility randomized clinical studies. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00150282
Volume :
121
Issue :
6
Database :
Academic Search Index
Journal :
Fertility & Sterility
Publication Type :
Academic Journal
Accession number :
177455055
Full Text :
https://doi.org/10.1016/j.fertnstert.2024.01.035