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Autopsy-Based Growth Charts May under-Detect Fetal Growth Restriction at Autopsy.
- Source :
-
Fetal & Pediatric Pathology . May/Jun2024, Vol. 43 Issue 3, p198-207. 10p. - Publication Year :
- 2024
-
Abstract
- Background: Accurate identification of fetal growth restriction in fetal autopsy is critical for assessing causes of death. We examined the impact of using a chart derived from ultrasound measurements of healthy fetuses (World Health Organization fetal growth chart) versus a chart commonly used by pathologists (Archie et al.) derived from fetal autopsy-based populations in diagnosing small-for-gestational-age (SGA) birth in perinatal deaths. Study Design: We examined perinatal deaths that underwent autopsy at BC Women's Hospital, 2015-2021. Weight centiles were assigned using the ultrasound-based fetal growth chart for birthweight and autopsy-based growth chart for autopsy weight. Results: Among 352 fetuses, 30% were SGA based on the ultrasound-based fetal growth chart versus 17% using the autopsy-based growth chart (p < 0.001). Weight centiles were lower when using the ultrasound-based versus autopsy-based growth chart (median difference of 9 centiles [IQR 2, 20]). Conclusions: Autopsy-based growth charts may under-classify SGA status compared to ultrasound-based fetal growth charts. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15513815
- Volume :
- 43
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Fetal & Pediatric Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 177396278
- Full Text :
- https://doi.org/10.1080/15513815.2023.2299491